Inventor · Wilmette, IL, US

Robert L. Letsinger

52Patents
37h-index
16Co-inventors
85Inventor score

Filing activity: Jun 14, 1984 → Feb 2, 2007

Most-cited inventions

PatentTitleAreaCited byStatus
US5476925A Oligodeoxyribonucleotides including 3'-aminonucleoside-phosphoramidate linkages and terminal 3'-amino groups Chemistry; Metallurgy 518 Expired
US6361944B1 Nanoparticles having oligonucleotides attached thereto and uses therefor Chemistry; Metallurgy 368 Expired
US4958013A Cholesteryl modified oligonucleotides Chemistry; Metallurgy 315 Expired
US5416203A Steroid modified oligonucleotides Chemistry; Metallurgy 275 Expired
US6506564B1 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 202 Expired
US5476930A Non-enzymatic ligation of oligonucleotides Chemistry; Metallurgy 173 Expired
US6750016B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 135 Expired
US6767702B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 134 Expired
US5780613A Covalent lock for self-assembled oligonucleotide constructs Chemistry; Metallurgy 131 Expired
US6417340B1 Nanoparticles having oligonucleotides attached thereto and uses therefor Chemistry; Metallurgy 123 Expired
US5681943A Method for covalently linking adjacent oligonucleotides Chemistry; Metallurgy 96 Expired
US6582921B2 Nanoparticles having oligonucleotides attached thereto and uses thereof Emerging Cross-Sectional Technologies 95 Expired
US6720411B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 88 Expired
US6682895B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 79 Expired
US6610491B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 75 Expired
US6495324B1 Nanoparticles having oligonucleotides attached thereto and uses therefor Chemistry; Metallurgy 74 Expired
US6773884B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 73 Expired
US6777186B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 69 Expired
US6759199B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 68 Expired
US6677122B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 66 Expired
US6709825B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 64 Expired
US7250499B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 58 Expired
US6602669B2 Method of detection by enhancement of silver staining Emerging Cross-Sectional Technologies 57 Expired
US5112962A Labile anchors for solid phase polynucleotide synthesis Emerging Cross-Sectional Technologies 57 Expired
US6645721B2 Nanoparticles having oligonucleotides attached thereto and uses therefor Emerging Cross-Sectional Technologies 53 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.