Nucleic acid multimers and amplified nucleic acid hybridization assays using same
US5124246A · kind A · utility
646Cited by
11References
59Claims
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Key dates
| Filing date | Apr 18, 1989 |
| Grant date | Jun 23, 1992 |
| Priority date | — |
| Expiry date | Apr 18, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.
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