Method of enhancing growth in patients using combination therapy
US5126324A · kind A · utility
82Cited by
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29Claims
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Assignee
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Key dates
| Filing date | Jun 7, 1990 |
| Grant date | Jun 30, 1992 |
| Priority date | — |
| Expiry date | Jun 7, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is disclosed for enhancing growth of a mammal by administration of a combination of effective amounts of IGF-I and GH so as to enhance the growth of the mammal over the enhancement in growth achieved using either IGF-I or GH alone in an amount equal to that used for either IGF-I or GH, respectively, in the combination. Preferably, the mammal is a child, the IGF-I is native-sequence, mature human IGF-I or human brain IGF-I, and the GH is native-sequence, mature human GH with or without a terminal methionine. In another preferred embodiment, the mammal is a non-human animal of economic importance such as a cow or pig.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.