Amino acid derivatives which have renin inhibiting activity
US5140011A · kind A · utility
10Cited by
7References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 29, 1990 |
| Grant date | Aug 18, 1992 |
| Priority date | — |
| Expiry date | Mar 29, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of the formula ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the significance given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharmaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.