Cloned genes encoding recombinant protein A
US5151350A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 27, 1982 |
| Grant date | Sep 29, 1992 |
| Priority date | — |
| Expiry date | Oct 27, 2002 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The gene coding for a protein A-like material has been successfully cloned and expressed for the first time. The cloning of this gene with its nucleotide sequence characterization, also disclosed, enables those skilled in the art to obtain quantities of a protein A-like material nucleotide sequence for cloning in various host-vector systems. Protein A is well known as a valuable component of a variety of diagnostic test systems. The protein A-like material of the subject invention, and subfragments thereof, have the protein A properties of binding to IgG at the Fc region and activation of polyclonal antibody synthesis. Thus, these entities are useful in the same manner as protein A.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.