Apparatus for countercurrent chromatography separations
US5169521A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 26, 1991 |
| Grant date | Dec 8, 1992 |
| Priority date | — |
| Expiry date | Nov 26, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/3046
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to an improved continuous countercurrent chromatography apparatus. The invention further relates to an improved method of countercurrent chromatography comprises filling a separation column with a first solvent, introducing into the column a sample solute to be separated, continuously pumping a second solvent into the column, the second solvent being substantially immiscible with the first solvent, maintaining the solvent flowing out of the column at a temperature effective to avoid clouding thereof, spectrophotometrically monitoring the temperature-maintained separating fractions flowing out of the column, and applying back-pressure to the solvent flowing into and out of the monitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.