Substituted phenserines as specific inhibitors of acetylcholinesterase
US5171750A · kind A · utility
33Cited by
3References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1991 |
| Grant date | Dec 15, 1992 |
| Priority date | — |
| Expiry date | Sep 26, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to substituted phenylcarbamate or naphthylcarbamate tricyclic compounds which provide highly potent and selective cholinergic agonist and blocking activity and their use as pharmaceutical agents. The invention further relates to improvements in therapy relative to cholinergic diseases such as glacuoma, Myasthenia Gravis, Alzheimer's disease and to improvements in therapy and organophosphate poisoning. The invention further provides for a selective acetylcholinesterase and butyrylcholinesterase agents and a method for inhibiting these esterases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.