Identification of a suppressor of atherogenic apolipoprotein

US5220006A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Robert Saxon Ross · Redmond, US
• Andrew Li · Sunnyvale, US
• Jeffrey M. Hoeg · Bethesda, US
• H. Bryan Brewer · Potomac, US

Key dates

• Filing date: Oct 23, 1990
• Grant date: Jun 15, 1993
• Expiry date: Oct 23, 2010

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A region in the apolipoprotein B gene has been identified that suppresses the transcription of apolipoprotein B. Polypeptides that bind to the suppressor region have been isolated.