Polymer reversal on solid surfaces
US5242974A · kind A · utility
264Cited by
5References
24Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 22, 1991 |
| Grant date | Sep 7, 1993 |
| Priority date | — |
| Expiry date | Nov 22, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for cyclization and reversal of the polarity of polymers on a substrate. The method provides for the formation of a polymer on a substrate (2) with a tether molecule (4). Through unmasking of a protective group (PG.sub.2) a cyclic polymer (6) is formed. Through cleavage of an appropriate bond, a polarity reversed polymer (8) is formed. The method finds particular application in the formation of, for example, peptides and oligonucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.