Patent assignee · NL · COMPANY

Affymax Technologies N.V.

88Patents
0Active
88Granted
41Portfolio score

Filing activity: Mar 7, 1990 → Feb 24, 2000

Most-cited patents

PatentTitleAreaCited byStatus
US5143854A Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof Emerging Cross-Sectional Technologies 1,974 Expired
US5445934A Array of oligonucleotides on a solid substrate Emerging Cross-Sectional Technologies 1,534 Expired
US5424186A Very large scale immobilized polymer synthesis Emerging Cross-Sectional Technologies 956 Expired
US5605793A Methods for in vitro recombination Chemistry; Metallurgy 862 Expired
US5580717A Recombinant library screening methods Chemistry; Metallurgy 849 Expired
US5830721A DNA mutagenesis by random fragmentation and reassembly Chemistry; Metallurgy 778 Expired
US5427908A Recombinant library screening methods Chemistry; Metallurgy 734 Expired
US5384261A Very large scale immobilized polymer synthesis using mechanically directed flow paths Emerging Cross-Sectional Technologies 698 Expired
US5811238A Methods for generating polynucleotides having desired characteristics by iterative selection and recombination Chemistry; Metallurgy 693 Expired
US5510270A Synthesis and screening of immobilized oligonucleotide arrays Emerging Cross-Sectional Technologies 665 Expired
US5547839A Sequencing of surface immobilized polymers utilizing microflourescence detection Physics 592 Expired
US5252743A Spatially-addressable immobilization of anti-ligands on surfaces Emerging Cross-Sectional Technologies 485 Expired
US5677195A Combinatorial strategies for polymer synthesis Emerging Cross-Sectional Technologies 466 Expired
US5405783A Large scale photolithographic solid phase synthesis of an array of polymers Emerging Cross-Sectional Technologies 445 Expired
US5545531A Methods for making a device for concurrently processing multiple biological chip assays Physics 444 Expired
US5412087A Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces Emerging Cross-Sectional Technologies 444 Expired
US5527681A Immobilized molecular synthesis of systematically substituted compounds Emerging Cross-Sectional Technologies 408 Expired
US5624711A Derivatization of solid supports and methods for oligomer synthesis Chemistry; Metallurgy 384 Expired
US5639603A Synthesizing and screening molecular diversity Chemistry; Metallurgy 370 Expired
US5324633A Method and apparatus for measuring binding affinity Emerging Cross-Sectional Technologies 361 Expired
US5571639A Computer-aided engineering system for design of sequence arrays and lithographic masks Chemistry; Metallurgy 317 Expired
US5451683A Spatially-addressable immobilization of anti-ligands on surfaces Emerging Cross-Sectional Technologies 279 Expired
US5549974A Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof Emerging Cross-Sectional Technologies 272 Expired
US5242974A Polymer reversal on solid surfaces Emerging Cross-Sectional Technologies 264 Expired
US5607691A Compositions and methods for enhanced drug delivery Human Necessities 255 Expired

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.