Camptothecin analogs as potent inhibitors of topoisomerase I
US5244903A · kind A · utility
56Cited by
6References
1Claims
0Family size
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Key dates
| Filing date | Oct 22, 1990 |
| Grant date | Sep 14, 1993 |
| Priority date | — |
| Expiry date | Oct 22, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for synthesizing camptothecin analogs using a novel hydroxyl-containing tricyclic intermediate and the camptothecin analogs produced by the process. The camptothecin analogs are effective inhibitors of topoisomerase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.