Antisense oligonucleotides for inhibiting herpesviruses
US5248670A · kind A · utility
108Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1990 |
| Grant date | Sep 28, 1993 |
| Priority date | — |
| Expiry date | Feb 26, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/16622
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antisense oligonucleotides are disclosed having a length of 15-30 nucleotides containing the CAT sequence and hybridizable to herpes simplex virus type I gene UL13, UL39, or UL40. These antisense oligomers inhibit the replication of the virus at least three-fold. Pharmaceutical compositions containing these oligonucleotides as the active ingredients are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.