Patent · US Expired

Ketamine analogues for treatment of thrombocytopenia

US5250732A · kind A · utility

45Cited by
3References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 18, 1991
Grant dateOct 5, 1993
Priority date
Expiry dateJul 18, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/16
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

5,6-Dehydronorketamine and derivatives retaining the .alpha.,.beta.-unsaturated carbonyl are disclosed. These and other Michael or Michael-type acceptors and adducts are shown to influence the replication, differentiation or maturation of blood cells, especially platelet progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.