Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones
US5254703A · kind A · utility
63Cited by
6References
13Claims
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Key dates
| Filing date | Apr 6, 1992 |
| Grant date | Oct 19, 1993 |
| Priority date | — |
| Expiry date | Apr 6, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D265/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing taxane derivatives taxol by providing a metal alkoxide having the bi, tri-, or tetracyclic taxane nucleus, reacting the metal alkoxide with an oxazinone to form an intermediate, and converting the intermediate to the taxane derivative.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.