Robert A. Holton
125Patents
26h-index
32Co-inventors
90Inventor score
Filing activity: Nov 2, 1987 → Aug 8, 2011
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5015744A | Method for preparation of taxol using an oxazinone | Emerging Cross-Sectional Technologies | 181 | Expired |
| US5175315A | Method for preparation of taxol using .beta.-lactam | Emerging Cross-Sectional Technologies | 145 | Expired |
| US5136060A | Method for preparation of taxol using an oxazinone | Emerging Cross-Sectional Technologies | 123 | Expired |
| US4876399A | Taxols, their preparation and intermediates thereof | Chemistry; Metallurgy | 115 | Expired |
| US5229526A | Metal alkoxides | Emerging Cross-Sectional Technologies | 114 | Expired |
| US5227400A | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them | Emerging Cross-Sectional Technologies | 111 | Expired |
| US5283253A | Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them | Emerging Cross-Sectional Technologies | 106 | Expired |
| US5430160A | Preparation of substituted isoserine esters using .beta.-lactams and metal or ammonium alkoxides | Emerging Cross-Sectional Technologies | 101 | Expired |
| US5243045A | Certain alkoxy substituted taxanes and pharmaceutical compositions containing them | Emerging Cross-Sectional Technologies | 88 | Expired |
| US5399726A | Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups | Chemistry; Metallurgy | 86 | Expired |
| US5350866A | 10-desacetoxytaxol derivatives | Chemistry; Metallurgy | 75 | Expired |
| US5250683A | Certain substituted taxanes and pharmaceutical compositions containing them | Emerging Cross-Sectional Technologies | 73 | Expired |
| US5274124A | Metal alkoxides | Emerging Cross-Sectional Technologies | 68 | Expired |
| US5466834A | Preparation of substituted isoserine esters using metal alkoxides and .beta . | Emerging Cross-Sectional Technologies | 67 | Expired |
| US5254703A | Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones | Chemistry; Metallurgy | 63 | Expired |
| US5405972A | Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes | Chemistry; Metallurgy | 58 | Expired |
| US5284864A | Butenyl substituted taxanes and pharmaceutical compositions containing them | Emerging Cross-Sectional Technologies | 53 | Expired |
| US5336785A | Method for preparation of taxol | Emerging Cross-Sectional Technologies | 53 | Expired |
| US5489601A | Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them | Chemistry; Metallurgy | 48 | Expired |
| US5284865A | Cyclohexyl substituted taxanes and pharmaceutical compositions containing them | Emerging Cross-Sectional Technologies | 47 | Expired |
| US5338872A | Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof | Chemistry; Metallurgy | 45 | Expired |
| US5539103A | .beta.-lactams as taxol intermediates N-acylated | Emerging Cross-Sectional Technologies | 44 | Expired |
| US5384399A | Oxazinone compounds for the preparation of taxol | Emerging Cross-Sectional Technologies | 41 | Expired |
| US5721268A | C7 taxane derivatives and pharmaceutical compositions containing them | Chemistry; Metallurgy | 39 | Expired |
| US5532363A | Heteroaryl substituted oxazinone compounds for the preparation of taxol | Emerging Cross-Sectional Technologies | 37 | Expired |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.