Photolabile reagents for incorporation into oligonucleotide chains
US5258506A · kind A · utility
318Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 25, 1989 |
| Grant date | Nov 2, 1993 |
| Priority date | — |
| Expiry date | Aug 25, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel photolabile photochemical reagents are disclosed. The reagents are useful in a variety of biochemical and chemical contexts, including nucleic hybridization assays and chemical phosphorylation of hydroxyl-containing compounds. The reagents are particularly useful for introducing cleavable sites into oligonucleotide or polynucleotide chains, i.e., sites which are cleavable upon photolysis. The reagents are also useful in both 5'- and 3'-phosphorylation of oligonucleotide or polynucleotide chains.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.