Pyrazines, pyrimidines and pyridazines useful in the treatment of senile dementia
US5260293A · kind A · utility
41Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 10, 1991 |
| Grant date | Nov 9, 1993 |
| Priority date | — |
| Expiry date | Oct 10, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides pyrazines, pyridazines or pyrimidines, or salts or prodrugs thereof, substituted on one of the ring carbon atoms thereof with a non-aromatic azacyclic or azabicyclic ring system; and independently substituted on each of the other ring carbon atoms with a substituent of low lipophilicity or a hydrocarbon substituent; which compounds stimulate central muscarinic acetylcholine receptors and therefore are useful in the treatment of neurological and mental illnesses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.