Acetic acid derivatives

US5273982A · kind A · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Leo Alig · Kaiseraugst, CH
• Albrecht Edenhofer · Basel, CH
• Marcel Muller · Frenkendorf, CH
• Arnold Trzeciak · Schopfheim, DE
• Thomas Weller · Binningen, CH

Key dates

• Filing date: Mar 5, 1991
• Grant date: Dec 28, 1993
• Expiry date: Mar 5, 2011

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Acetic acid derivatives of formula EQU H.sub.2 N(NH)C--X--Y--CO--Z--CH(Q.sup.1)COOQ.sup.2 I and hydrates, solvates and physiologically acceptable salts thereof are useful to inhibit the binding of adhesive proteins to blood platelets and also to inhibit blood platelet aggregation and cell-cell adhesion.