Amino acid derivatives useful as renin inhibitors
US5278161A · kind A · utility
5Cited by
2References
55Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 5, 1992 |
| Grant date | Jan 11, 1994 |
| Priority date | — |
| Expiry date | Nov 5, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein A, B, X, Y, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are as set forth in the specification, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diasteromeric racemates as well as pharmaceutically acceptable salts thereof which inhibit the activity of the natural enzyme renin and are useful in the control or prevention of high blood pressure and cardiac insufficiency are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.