Immobilized metal aqueous two-phase extraction and precipitation
US5283339A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 5, 1992 |
| Grant date | Feb 1, 1994 |
| Priority date | — |
| Expiry date | Aug 5, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/33303
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Metallated compounds can be used to extract or precipitate proteins from solution. The compounds can be polymers, such as polyalkylene glycols, which can be mono- or bimetallated or smaller bis-metal chelates, such as ethylenebis(oxyethylenenitrilo)tetraacetic acid. The monometallated polymers are preferred in the extraction process whereas the bimetallated compounds are preferred in the precipitation process. In addition, new PEG compounds which are capable of chelating a variety of metals are described. Both mono- and bi-metallated forms are set forth. The new metallated compounds are very effective in extracting or precipitating proteins from solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.