Inventor · Pasadena, CA, US

Frances H. Arnold

71Patents
17h-index
75Co-inventors
87Inventor score

Filing activity: Feb 1, 1991 → Nov 10, 2022

Most-cited inventions

PatentTitleAreaCited byStatus
US6540895B1 Microfabricated cell sorter for chemical and biological materials Physics 495 Expired
US6063637A Sensors for sugars and other metal binding analytes Emerging Cross-Sectional Technologies 425 Expired
US6537746B2 Method for creating polynucleotide and polypeptide sequences Chemistry; Metallurgy 220 Expired
US6153410A Recombination of polynucleotide sequences using random or defined primers Chemistry; Metallurgy 91 Expired
US5316935A Subtilisin variants suitable for hydrolysis and synthesis in organic media Chemistry; Metallurgy 85 Expired
US6177263A Recombination of polynucleotide sequences using random or defined primers Chemistry; Metallurgy 59 Expired
US7214298B2 Microfabricated cell sorter Physics 57 Expired
US5786428A Adsorbents for amino acid and peptide separation Performing Operations; Transporting 55 Expired
US5945325A Thermally stable para-nitrobenzyl esterases Chemistry; Metallurgy 51 Expired
US5310648A Composition of matter comprising an imprinted matrix exhibiting selective binding interactions through chelated metals Physics 49 Expired
US5741691A Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media Chemistry; Metallurgy 43 Expired
US5283339A Immobilized metal aqueous two-phase extraction and precipitation Chemistry; Metallurgy 40 Expired
US8361769B1 Regioselective alkane hydroxylation with a mutant CYP153A6 enzyme Emerging Cross-Sectional Technologies 30 Active
US7524664B2 Regio- and enantioselective alkane hydroxylation with modified cytochrome P450 Chemistry; Metallurgy 28 Expired
US5616790A Lipid-based metal sensor Physics 26 Expired
US7226768B2 Cytochrome P450 oxygenases Emerging Cross-Sectional Technologies 21 Expired
US6524837B1 Hydantoinase variants with improved properties and their use for the production of amino acids Chemistry; Metallurgy 18 Expired
US6361988B1 ECB deacylase mutants Chemistry; Metallurgy 14 Expired
US7115403B1 Directed evolution of galactose oxidase enzymes Chemistry; Metallurgy 12 Expired
US7098010B1 Directed evolution of oxidase enzymes Chemistry; Metallurgy 12 Expired
US6902918B1 Oxygenase enzymes and screening method Physics 11 Expired
US7435570B2 Thermostable peroxide-driven cytochrome P450 oxygenase variants and methods of use Chemistry; Metallurgy 11 Expired
US8097440B1 Engineered microorganisms capable of producing target compounds under anaerobic conditions Emerging Cross-Sectional Technologies 11 Active
US7863030B2 Regio- and enantioselective alkane hydroxylation with modified cytochrome P450 Chemistry; Metallurgy 10 Active
US7465567B2 Peroxide-driven cytochrome P450 oxygenase variants Chemistry; Metallurgy 10 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.