Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
US5315015A · kind A · utility
44Cited by
4References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 1992 |
| Grant date | May 24, 1994 |
| Priority date | — |
| Expiry date | Nov 10, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/582
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Compounds of the formula ##STR1## wherein F is a fluorescing compound; Y is --NH-- or a single covalent bond; Z is a straight or branched alkylene chain of 2 to 10 carbon atoms which is substituted by at least one hydrophilic group; Q is oxygen or sulfur; and X is a ligand-analog, the ligand-analog capable of being recognized by an antibody specific to the corresponding ligand. These compounds have improved properties in fluorescence polarization immunoassays by possessing either a better intensity and/or a larger span.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.