Hydroxamic derivatives and pharmaceutical compositions
US5318964A · kind A · utility
13Cited by
1References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 1993 |
| Grant date | Jun 7, 1994 |
| Priority date | — |
| Expiry date | May 24, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Hydroxamic acid derivatives of the formula ##STR1## and pharmaceutically acceptable salts thereof, which are collagenase inhibitors useful for the control or prevention of degenerative joint diseases, such as, rheumatoid arthritis and osteoarthritis or for the treatment of invasive tumors, atherosclerosis or multiple sclerosis, are described. Said compounds can be prepared either by hydroxamidating a corresponding carboxylic acid or deprotecting a corresponding benzyloxycarbamoyl compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.