Molecular encapsulation and delivery of alkenes alkynes and long chain alkanes, to living mammalian cells
US5321014A · kind A · utility
9Cited by
14References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 28, 1991 |
| Grant date | Jun 14, 1994 |
| Priority date | — |
| Expiry date | Jun 28, 2011 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A complex of a cyclodextrin and an alkane, alkene, alkyne, aromatic compound, etc. can be prepared according to the method of the present invention. These complexes can be delivered to prokaryotic and eukaryotic cells, tissues, and organs in vitro and in vivo. In this manner, the toxic, genotoxic, and mitogenic effects of these compounds can be determined. Ternary complexes further including one or more biologically active molecules in addition to an alkane, etc. can be employed to determine the modulatory effects of such biologically active molecules on these alkanes, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.