Composition useful for the fabrication of vaccines
US5324513A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Feb 28, 1991 |
| Grant date | Jun 28, 1994 |
| Priority date | — |
| Expiry date | Feb 28, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/108
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns a composition useful for the manufacture of vaccines containing particles having the immunogenic properties characteristic of the antigen HBsAg, these particles being more particularly characterized by the fact that the said particles equally contain a receptor for polymerized human albumin. They are obtained by transformation of human or animal cells by a vector containing a DNA sequence coding for the S and pre-S regions of a genome of viral hepatitis B, this DNA sequence being placed under the direct control of a promoter permitting the effective transcription of the said sequence in the human or animal cells transformable by the said vector.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.