Patent · US Expired

CD4 adheson variants

US5336603A · kind A · utility

225Cited by
11References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 26, 1992
Grant dateAug 9, 1994
Priority date—
Expiry dateAug 26, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel derivatives of cell surface proteins which are homologous to the immunoglobulin superfamily (adhesons) are provided. Amino acid sequence variations are introduced into adheson, the most noteworthy of which are those in which the transmembrane and, preferably, cytoplasmic domains are rendered functionally inactive, and in which adheson extracellular domains replace an immunoglobulin variable region. These variants are useful in therapy or diagnostics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.