Peptide library and screening method
US5338665A · kind A · utility
147Cited by
3References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1992 |
| Grant date | Aug 16, 1994 |
| Priority date | — |
| Expiry date | Oct 15, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1075
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a DNA binding protein and a random peptide and also contain a binding site for the DNA binding protein can be used to screen for novel ligands. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand and to the recombinant DNA vector through the DNA binding protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.