DNA encoding polypeptides with activity against gram-positive and gram-negative bacteria
US5344765A · kind A · utility
9Cited by
7References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 28, 1993 |
| Grant date | Sep 6, 1994 |
| Priority date | — |
| Expiry date | Jan 28, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to cecropin-like polypeptides with a variety of C-terminus modifications. Conversion of the terminal carboxy group to a homoserine extended neutral, negatively charged or positively charged form results in the polypeptides of the invention that have significant bactericidal effects against both Gram-positive and Gram-negative bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.