Cyclobutyl oligonucleotide surrogates
US5359044A · kind A · utility
442Cited by
2References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 13, 1991 |
| Grant date | Oct 25, 1994 |
| Priority date | — |
| Expiry date | Dec 13, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Oligonucleotide surrogates comprising a plurality of cyclobutyl moieties covalently joined by linking moieties are prepared and used as antisense diagnostics and research reagents. Methods of synthesis and use of both the oligonucleotide surrogates and intermediates thereof are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.