Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5359100A · kind A · utility
33Cited by
1References
13Claims
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Key dates
| Filing date | Aug 13, 1993 |
| Grant date | Oct 25, 1994 |
| Priority date | — |
| Expiry date | Aug 13, 2013 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Linear or branched oligonucleotide multimers useful as amplifiers in biochemical assays which comprise (1) at least one first single-stranded oligonucleotide unit that is complementary to a single-stranded oligonucleotide sequence of interest, and (2) a multiplicity of second single-stranded oligonucleotide units that are complementary to a single-stranded labeled oligonucleotide. Amplified sandwich nucleic acid hybridizations and immunoassays using the multimers are exemplified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.