Ketamine analogues for treatment of thrombocytopenia
US5384331A · kind A · utility
25Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 28, 1993 |
| Grant date | Jan 24, 1995 |
| Priority date | — |
| Expiry date | May 28, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
5,6-Dehydronorketamine and derivatives retaining the .alpha.,.beta.-unsaturated carbonyl are disclosed. These end other Michael or Michael-type acceptors and adducts are shown to influence the replication, differentiation or maturation of blood cells, especially platelet progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.