New linker for bioactive agents
US5387578A · kind A · utility
35Cited by
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29Claims
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Key dates
| Filing date | Apr 3, 1992 |
| Grant date | Feb 7, 1995 |
| Priority date | — |
| Expiry date | Apr 3, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/24
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Conjugate of general formula 1: EQU [A--O--W-Z].sub.a -T 1 wherein the moity A--O--is the residue of drug of formula A--O--H in which --O--H is a primary or secondary hydroxyl group; a is an integer of from 1 to 30; W is a group of general formula 2: ##STR1## wherein b is an integer of from 1 to 4, B represents a C.sub.1 -C.sub.3 alkylene group and R.sub.1 and R.sub.2 each independently represent hydrogen, halogen, alkyl, phenyl or substituted phenyl; Z is a spacer group and T is a carrier moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.