Amino acid derivatives having renin inhibiting activity
US5393875A · kind A · utility
6Cited by
2References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 3, 1993 |
| Grant date | Feb 28, 1995 |
| Priority date | — |
| Expiry date | Aug 3, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds of the formula ##STR1## wherein A, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the significance given in claim 1, in the form of optically pure diastereomers, mixtures of diastereomers, diastereomeric racemates or mixtures of diastereomeric racemates as well as pharmaceutically usable salts thereof inhibit the activity of the natural enzyme renin and can accordingly be used in the form of pharamaceutical preparations in the control or prevention of high blood pressure and cardiac insufficiency. They can be manufactured according to various methods which are known per se.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.