Patent · US Expired

Method of making asymmetric de ring intermediates for the synthesis of camptothecin and camptothecin analogs

US5395939A · kind A · utility

3Cited by
8References
7Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 30, 1993
Grant dateMar 7, 1995
Priority date
Expiry dateNov 30, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Methods of making asymmetric DE ring intermediates for the synthesis of camptothecin and camptothecin analogs employ a dioxane intermediate as the immediate precursor to the DE ring intermediate. Novel intermediates are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.