Serine protease variants having peptide ligase activity
US5403737A · kind A · utility
26Cited by
2References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1993 |
| Grant date | Apr 4, 1995 |
| Priority date | — |
| Expiry date | Feb 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P21/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to serine protease variants derived from precursor serine proteases via recombinant and/or chemical methods to form protease variants having improved peptide ligase activity. The invention also includes novel ligation substrates which in combination with the serine protease variants and a second ligation substrate are capable of forming a ligation product. The invention also relates to methods for forming such ligation products and the products formed thereby.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.