Patent · US Expired

Vitamin D3 fluorinated analogs

US5428029A · kind A · utility

39Cited by
8References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 24, 1993
Grant dateJun 27, 1995
Priority date
Expiry dateNov 24, 2013

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## wherein R is hydrogen, hydroxy, or fluorine, X is H.sub.2 or .dbd.CH.sub.2, and the 23,24-double bond is E or Z, are useful as agents for the treatment of hyperproliferative disorders of the skin such as psoriasis, as agents for the treatment of tumors such as breast cancer, as agents for the treatment of neoplastic diseases such as leukemia, and as agents for the treatment of sebaceous gland diseases such as acne and seborrheic dermatitis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.