High efficiency fluorescence flow cell for capillary liquid chromatography or capillary electrophoresis
US5430541A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 12, 1993 |
| Grant date | Jul 4, 1995 |
| Priority date | — |
| Expiry date | Jan 12, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/0642
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A fluorescence flow cell having a capillary through which a sample fluid is moved, an optical source that directs an exposing beam of light through the sample fluid, a collector that collects fluorescent light from the exposed region of the sample and directs such collected light to a detector. A beam blocker prevents light that is scattered by the capillary walls from reaching the detector, thereby improving the signal-to-noise ratio of the system. The beam blocker also has a pair of legs that prevent the sample fluid from being exposed by either the exposing light or the collected light outside of the exposing region. The structure of the components enables the various components to be quickly and accurately assembled and enables easy replacement of the capillary.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.