Pyrrolo-pyridine derivatives
US5432177A · kind A · utility
58Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1994 |
| Grant date | Jul 11, 1995 |
| Priority date | — |
| Expiry date | Feb 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A class of pyrrolo[2,3-b]pyridine derivatives, substituted at the 3-position by a substituted piperazinylmethyl moiety, are antagonists of dopamine receptor subtypes within the brain, having a selective affinity for the dopamine D.sub.4 receptor subtype over other dopamine receptor subtypes, and are accordingly of benefit in the treatment and/or prevention of psychotic disorders such as schizophrenia while manifesting fewer side-effects than those associated with classical neuroleptic drugs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.