2'3'-dideoxy-2',3'-didehydro-7,8-disubstituted guanosines and their immunostimulative effect
US5441942A · kind A · utility
5Cited by
5References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 27, 1994 |
| Grant date | Aug 15, 1995 |
| Priority date | — |
| Expiry date | May 27, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Immunostimulating 7,8-disubstituted guanine derivatives that also contain a .beta.-9,1'-linked-2',3'-dideoxy-2',3'-didehydroribosyl substituent are disclosed whose structures are represented by Formula I ##STR1## wherein X is O or S; R.sup.1 is a hydrocarbyl or substituted hydrocarbyl moiety having a length of about one to about seven carbon atoms; R.sup.2 is hydrogen or C.sub.1 -C.sub.8 acyl; and the pharmaceutically acceptable base addition salts thereof. Also disclosed are compositions containing an immunostimulating guanine derivative and processes for using the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.