Method for interfacing liquid chromatography-mass spectrometry systems
US5447553A · kind A · utility
8Cited by
6References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1994 |
| Grant date | Sep 5, 1995 |
| Priority date | — |
| Expiry date | Oct 19, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/7273
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Close coupled momentum separator with integral removable source volume for particle beam liquid chromatography/mass spectrometry is provided. The inventive PB LC/MS system comprises a momentum separator wherein the skimmers are designed to accommodate the particle beam conical dispersion so as to minimize the number of particles lost in the separator. In addition, the exit of the momentum separator is closely coupled to the entrance of the MS source volume. The PB LC/MS system demonstrates improved linearity in signal and enhanced sensitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.