James Apffel
25Patents
10h-index
23Co-inventors
75Inventor score
Filing activity: Feb 25, 1987 → May 14, 2020
Most-cited inventions
| Patent | Title | Area | Cited by | Status |
|---|---|---|---|---|
| US5716825A | Integrated nucleic acid analysis system for MALDI-TOF MS | Performing Operations; Transporting | 397 | Expired |
| US5705813A | Integrated planar liquid handling system for maldi-TOF MS | Physics | 257 | Expired |
| US5750988A | Orthogonal ion sampling for APCI mass spectrometry | Physics | 153 | Expired |
| US5495108A | Orthogonal ion sampling for electrospray LC/MS | Electricity | 68 | Expired |
| US6607644B1 | Microanalytical device containing a membrane for molecular identification | Physics | 57 | Expired |
| US5331159A | Combined electrospray/particle beam liquid chromatography/mass spectrometer | Physics | 30 | Expired |
| US6649908B2 | Multiplexing capillary array for atmospheric pressure ionization-mass spectrometry | Physics | 26 | Expired |
| US6284115A | In-line flow through micro-dialysis apparatus and method for high performance liquid phase separations | Physics | 23 | Expired |
| USRE36892E | Orthogonal ion sampling for electrospray .[.LC/MS.]. mass spectrometry | General | 17 | Expired |
| US6294779A | Orthogonal ion sampling for APCI mass spectrometry | Electricity | 17 | Expired |
| US5447553A | Method for interfacing liquid chromatography-mass spectrometry systems | Physics | 8 | Expired |
| US5223131A | Apparatus for interfacing liquid chromatography-mass spectrometry systems | Physics | 7 | Expired |
| US6278110A | Orthogonal ion sampling for APCI mass spectrometry | Physics | 6 | Expired |
| US6639216B2 | Orthogonal ion sampling for APCI mass spectrometry | Electricity | 5 | Expired |
| US8642744B2 | Crosslinking reagent for analysis of protein-protein interaction | Physics | 5 | Active |
| US6498343B2 | Orthogonal ion sampling for APCI mass spectrometry | Electricity | 5 | Expired |
| US6797946B2 | Orthogonal ion sampling for APCI mass spectrometry | Electricity | 5 | Expired |
| US6379889B1 | Multiplexing methods for identifying nucleic acids using denaturing liquid chromatography | Emerging Cross-Sectional Technologies | 5 | Expired |
| US4784962A | Mixture of amino acid derivatives, process of producing the mixture and use of the mixture for quantitative determination of the amino acids | Emerging Cross-Sectional Technologies | 3 | Expired |
| US9543137B2 | Sample droplet generation from segmented fluid flow and related devices and methods | Physics | 3 | Active |
| US10012574B2 | Method for metabolomic sample preparation based on ionic liquid dispersive liquid-liquid microextraction | Physics | 1 | Active |
| US7425451B2 | Triazine derivatives as universal peptide isotope tag reagents (U-PIT) | Chemistry; Metallurgy | 0 | Expired |
| US11808675B2 | Room temperature methods for preparing biological analytes | Chemistry; Metallurgy | 0 | Active |
| US7109040B2 | Modular isotope coding approach to proteomic analysis | Emerging Cross-Sectional Technologies | 0 | Expired |
| US9958363B2 | Fluorous affinity extraction for ionic liquid-based sample preparation | Emerging Cross-Sectional Technologies | 0 | Active |
Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.