Method of treating joint disorders using hydroxamic derivatives
US5447929A · kind A · utility
10Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 1994 |
| Grant date | Sep 5, 1995 |
| Priority date | — |
| Expiry date | Mar 17, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Hydroxamic acid derivatives of the fdrrnula ##STR1## and pharmaceutically acceptable salts thereof, which are collagenase inhibitors useful for the control or prevention of degenerative joint diseases, such as, rheumatoid arthritis and ostecarthritis or for the treatment of invasive tumours, atherosclerosis or multiple sclerosis, are described. Said compounds can be prepared either by hyclroxamidating a corresponding carboxylic acid or deprotecting a corresponding benzyloxycarbamoyl compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.