Methods and reagents for HLA class I A locus DNA typing
US5451512A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 28, 1993 |
| Grant date | Sep 19, 1995 |
| Priority date | — |
| Expiry date | Sep 28, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Primers for amplification of specific nucleic acid sequences of the second and third exon of HLA Class I A gene and probes for identifying polymorphic sequences contained in the amplified DNA can be used in processes for typing homozygous or heterozygous samples from a variety of sources and for detecting allelic variants not distinguishable by serological methods. This HLA-A DNA typing system can be used in a forward or reverse dot-blot format that is simple and rapid to perform, produces detectable signals in minutes, and can be used for tissue typing, determining individual identity, and identifying disease susceptible individuals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.