DNA encoding chimeric polypeptides comprising the interleukin-5 receptor .alpha.-chain fused to immunoglobulin heavy chain constant regions
US5455337A · kind A · utility
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18Claims
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Key dates
| Filing date | Sep 16, 1992 |
| Grant date | Oct 3, 1995 |
| Priority date | — |
| Expiry date | Sep 16, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Chimeric polypeptides encoded by a DNA sequence having a first DNA subsequence coding for a fragment of at least one of the .alpha.- and/or .beta.-chain of the human interleukin-5 receptor, and a second DNA subsequence coding for the constant domains of a heavy- or a light-chain of a human immunoglobulin, or a fragment thereof are useful in treating illnesses with demonstrated eosinophilia.
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