Substituted benzimidazolyl derivatives and pharmaceutical compositions containing these compounds

US5459147A · kind A · utility

Assignee

• Dr. Karl Thomae GmbH · DE

Inventors

• Norbert Hauel · Schemmerhofen, DE
• Uwe Ries · Biberach an der Riß, DE
• Berthold Narr · Biberach, DE
• Jacques van Meel · Mittelbiberach, DE
• Wolfgang Wienen · Äpfingen, DE
• Michael Entzeroth · Warthausen, DE

Key dates

• Filing date: May 3, 1994
• Grant date: Oct 17, 1995
• Expiry date: May 3, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to substituted benzimidazolyl derivatives of the general formula ##STR1## wherein A and R.sub.a to R.sub.c are defined as in claim 1, the mixtures of position isomers thereof and the salts thereof which have valuable properties. These compounds have valuable pharmacological properties, particularly angiotensin-antagonistic effects and preferably angiotensin-II-antagonistic effects.