Imidazolyl-substituted phenylacetic acid prolinamides

US5459156A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Matthias Muller-Gliemann · Haan, DE
• Jurgen Dressel · Radevormwald, DE
• Peter Fey · Wuppertal, DE
• Rudolf Hanko · Düsseldorf, DE
• Walter Hubsch · Wuppertal, DE
• Thomas Kramer · Wuppertal, DE
• Ulrich Muller · Wuppertal, DE
• Martin Beuck · Milford, US
• Stanislav Kazda · Wuppertal, DE
• Stefan Wohlfeil · Hilden, DE
• Andreas Knorr · Erkrath, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Siegfried Zaiss · Wuppertal, DE

Key dates

• Filing date: Jan 27, 1994
• Grant date: Oct 17, 1995
• Expiry date: Jan 27, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Imidazolyl-substituted phenylacetic acid prolinamides are prepared by reacting corresponding imidazolyl-substituted phenylacetic acids with prolines. The imidazolyl-substituted phenylacetic acid prolinamides can be used as active compounds in medicaments, preferably for the treatment of hypertension and atherosclerosis.