Biopolymer synthesis apparatus and method
US5462748A · kind A · utility
8Cited by
7References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 14, 1994 |
| Grant date | Oct 31, 1995 |
| Priority date | — |
| Expiry date | Jan 14, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B60/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A cartridge containing a dry polymer composition carrying trapped biopolymer subunits for use in synthesis of biopolymer chains provides a discrete unit for stepwise supply of subunits, such as protected amino acids, in an automated apparatus for biopolymer synthesis. The composition is swellable in organic solvent to release and supply the subunits to a growing biopolymer chain immobilized on a polymer support. An automated synthesizer uses the cartridges for sequential subunit supply and monitors conductivity of deprotection reagents to control cycling and timing of steps.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.