Inhibition of Mac-1 receptor binding to fibrinogen using D.sub.30 homologs
US5473051A · kind A · utility
7Cited by
1References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 18, 1991 |
| Grant date | Dec 5, 1995 |
| Priority date | — |
| Expiry date | Jul 18, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention contemplates therapeutic compositions containing a D.sub.30 homolog capable of binding to the Mac-1 receptor D.sub.30 binding site and inhibiting fibrinogen binding to the Mac-1 receptor via the D.sub.30 binding site, Methods of inhibiting Mac-1 receptor binding to any Mac-1 ligand and methods of inhibiting Mac-1 receptor mediated inflammation within a patient by administering a D.sub.30 homolog are also contemplated,
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.