Retroviral protease inhibitors

US5482947A · kind A · utility

Inventors

• John J. Talley · Chesterfield, US
• Daniel P. Getman · Chesterfield, US
• Gary A. DeCrescenzo · Holden, US
• Ko-Chung Lin · Lexington, US
• Michael L. Vazquez · Saint Louis, US
• Richard A. Mueller · Glencoe, US
• Kathryn L. Reed · Raleigh, US
• Robert M. Heintz · Ballwin, US
• Michael Clare · Skokie, US
• John N. Freskos · Clayton, US
• Eric T. Sun · Singapore, SG

Key dates

• Filing date: Nov 15, 1993
• Grant date: Jan 9, 1996
• Expiry date: Nov 15, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Urea-containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.