Plant protein useful for treating tumors and HIV infection

US5484889A · kind A · utility

Assignees

• NEW YORK UNIVERSITY · US
• American BioScience, Inc. · US
• The United States of America as Represented by the Secretary of the Department of Health and Human Services · US

Inventors

• Sylvia Lee-Huang · New York, US
• Philip L. Huang · Boston, US
• Peter L. Nara · Frederick, US
• Hao-chia Chen · Potomac, US
• Hsiang-Fu Kung · Verona, US
• Peter Huang · New York, US
• Henry Huang · New York, US
• Paul Huang · Boston, US

Key dates

• Filing date: Jul 21, 1994
• Grant date: Jan 16, 1996
• Expiry date: Jul 21, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A protein, in particular MAP 30, obtainable from both the fruit and seeds of Momordica charantia or produced by recombinant means useful for treating tumors and HIV infections is disclosed. In treating HIV infections, the protein is administered alone or in conjunction with conventional AIDS therapies. Also provided are processes for purifying the protein, DNA sequences encoding the protein, and recombinant DNA methods for expressing the protein.